Ranking · Flanders · NACE 21
Manufacture of basic pharmaceutical products and pharmaceutical preparations: the largest companies in Flanders
As of 13 Nov 2026, 281 companies in Manufacture of basic pharmaceutical products and pharmaceutical preparations (NACE 21) in Flanders publish total assets in recent accounts (financial years 2023 to 2026). The top 10 account for €26.8bn, out of €27.6bn for all of them; median total assets are 559,056 €. Janssen Pharmaceutica leads with €21.6bn (financial year 2025).
Top 50 · Manufacture of basic pharmaceutical products and pharmaceutical preparations · Flanders
Ranked by total assets in the latest filed accounts. This is a size criterion, not an assessment.
| # | Company | Total assets | Revenue | Equity | FTE | Year |
|---|---|---|---|---|---|---|
| 1 | Janssen Pharmaceutica 2340 Beerse | €21.6bn | €21.8bn | €11.7bn | 5,324.5 | 2025 |
| 2 | Pfizer Manufacturing Belgium 2870 Puurs-Sint-Amands | €2.46bn | €1.02bn | €1.89bn | 4,020.8 | 2025 |
| 3 | Genzyme Flanders 2440 Geel | €1.00bn | €457.2m | €862.1m | 990.1 | 2025 |
| 4 | Ajinomoto Omnichem 9230 Wetteren | €476.3m | €468.2m | €323.9m | 863.4 | 2026 |
| 5 | Organon Heist 2220 Heist-op-den-Berg | €349.6m | €287.4m | €235.2m | 1,004.9 | 2025 |
| 6 | Novartis Manufacturing 2870 Puurs-Sint-Amands | €285.2m | €256.5m | €148.4m | 980.0 | 2025 |
| 7 | Vision Healthcare 8560 Wevelgem | €283.8m | €14.3m | €153.7m | — | 2025 |
| 8 | JNTL Consumer Health (Belgium) 2000 Antwerp | €156.0m | €217.6m | €133.4m | 23.1 | 2025 |
| 9 | PanTera 2400 Mol | €115.8m | €13.3m | €108.8m | 24.2 | 2025 |
| 10 | Alcon Laboratories Belgium 2870 Puurs-Sint-Amands | €107.2m | €169.7m | €26.6m | 401.8 | 2025 |
| 11 | Mecs Europe/Africa 1560 Hoeilaart | €72.9m | €44.9m | €44.1m | 23.7 | 2025 |
| 12 | KELA - Kempisch Laboratorium - Kela Laboratoria 2320 Hoogstraten | €63.2m | €55.2m | €31.9m | 261.4 | 2025 |
| 13 | Laboratoria Qualiphar 2880 Bornem | €50.8m | €44.9m | €25.6m | 186.1 | 2025 |
| 14 | Namsa Belgium 3290 Diest | €41.5m | 421,384 € | €5.29m | 5.1 | 2025 |
| 15 | Medgenix Benelux 8560 Wevelgem | €39.4m | €42.9m | €17.5m | 122.3 | 2025 |
| 16 | Purna Pharmaceuticals 2870 Puurs-Sint-Amands | €34.3m | €43.2m | €19.4m | 182.6 | 2025 |
| 17 | Opella Healthcare Belgium NV/SA 1831 Machelen (Brab.) | €32.3m | €36.2m | €20.7m | 39.1 | 2025 |
| 18 | invoX Belgium 3590 Diepenbeek | €29.2m | — | −€64.6m | 45.5 | 2025 |
| 19 | V.M.D. 2370 Arendonk | €28.5m | €40.6m | €2.73m | 50.5 | 2025 |
| 20 | Orfit Industries 2110 Wijnegem | €24.9m | €31.0m | €18.4m | 78.3 | 2025 |
| 21 | Sanico 2300 Turnhout | €24.2m | €22.3m | €13.3m | 87.1 | 2025 |
| 22 | Bio Minerals 9070 Destelbergen | €17.7m | — | €11.9m | 18.8 | 2025 |
| 23 | Conforma 9070 Destelbergen | €16.3m | — | €4.06m | 97.0 | 2025 |
| 24 | Delaval 9031 Ghent | €16.0m | €43.4m | €2.36m | 65.5 | 2025 |
| 25 | Flen Health Pharma 2550 Kontich | €15.6m | €12.7m | €14.5m | 29.9 | 2025 |
| 26 | Conceptual Development 2018 Antwerp | €13.5m | — | €11.3m | — | 2024 |
| 27 | Upjohn 1560 Hoeilaart | €12.3m | — | €12.1m | — | 2025 |
| 28 | Achtendries 9040 Ghent | €9.79m | 259,148 € | €3.22m | — | 2024 |
| 29 | Ziphius 9052 Ghent | €9.49m | — | €5.90m | 41.2 | 2025 |
| 30 | Laboratoria Wolfs 2070 Beveren-Kruibeke-Zwijndrecht | €6.74m | €12.2m | €2.46m | 48.2 | 2025 |
| 31 | Deba Pharma 8510 Kortrijk | €6.57m | — | €6.20m | 1.2 | 2025 |
| 32 | Avondvrede 1630 Linkebeek | €6.43m | — | 751,439 € | — | 2025 |
| 33 | Obulytix 9052 Ghent | €5.29m | — | €2.22m | 4.3 | 2025 |
| 34 | Perseus Biomics 3001 Leuven | €5.25m | — | €2.06m | 14.3 | 2025 |
| 35 | Teuvan 3720 Hasselt | €4.91m | — | €2.47m | — | 2025 |
| 36 | Mondomed 3930 Hamont-Achel | €4.65m | — | €2.48m | — | 2025 |
| 37 | Immo Vandemoortele 8980 Zonnebeke | €4.53m | — | €4.21m | — | 2025 |
| 38 | Advanced Practical Diagnostics 2300 Turnhout | €4.50m | — | €2.50m | 12.3 | 2025 |
| 39 | MeiraGTx Belgium 9052 Ghent | €4.44m | — | 615,562 € | 5.5 | 2025 |
| 40 | Lifrank 8750 Wingene | €4.07m | — | €2.60m | — | 2025 |
| 41 | remedent 9000 Ghent | €4.04m | 62,168 € | €2.26m | 2.6 | 2025 |
| 42 | Idevax 2110 Wijnegem | €3.95m | — | €2.29m | 4.9 | 2025 |
| 43 | MAATSCHAPPIJ voor INVESTERING en BEDRIJFSONTWIKKELING 1770 Liedekerke | €3.93m | — | €2.90m | — | 2025 |
| 44 | Elster-Instromet Invest 2910 Essen | €3.78m | — | €3.72m | — | 2025 |
| 45 | Laboratoria Bota 9800 Deinze | €3.62m | — | 692,848 € | 40.1 | 2025 |
| 46 | Investerings- Beheer- en Studievennootschap 1853 Grimbergen | €3.47m | — | €1.12m | — | 2025 |
| 47 | AnimAb 9052 Ghent | €3.47m | — | €2.76m | 5.6 | 2025 |
| 48 | Temmune Therapeutics 2800 Mechelen | €3.43m | — | €2.01m | — | 2025 |
| 49 | Lefimo 8301 Knokke-Heist | €3.43m | — | €3.36m | — | 2025 |
| 50 | Dr. Naesens en Dr. Kaes 3500 Hasselt | €3.39m | — | €3.30m | — | 2025 |
Ranking based on each company's own annual accounts (statutory, not consolidated): a subsidiary and its parent appear separately, and the ranking differs from lists based on consolidated group accounts.
“—”: not published. Small companies (micro and abridged accounts) do not have to publish their revenue.
Manufacture of basic pharmaceutical products and pharmaceutical preparations across Belgium → All sectors · Flanders →
Other sectors · Flanders
- 01 Crop and animal production, hunting and related service activities5,114
- 02 Forestry and logging186
- 03 Fishing and aquaculture102
- 08 Other mining and quarrying88
- 09 Mining support service activities32
- 10 Manufacture of food products3,220
- 11 Manufacture of beverages386
- 12 Manufacture of tobacco products16
- 13 Manufacture of textiles704
- 14 Manufacture of wearing apparel299
- 15 Manufacture of leather and related products of other materials50
- 16 Manufacture of wood and of products of wood and cork, except furniture; manufacture of articles of straw and plaiting materials1,102
- 17 Manufacture of paper and paper products196
- 18 Printing and reproduction of recorded media1,328
- 19 Manufacture of coke and refined petroleum products18
- 20 Manufacture of chemicals and chemical products539
- 22 Manufacture of rubber and plastic products561
- 23 Manufacture of other non-metallic mineral products952
- 24 Manufacture of basic metals244
- 25 Manufacture of fabricated metal products, except machinery and equipment4,115
- 26 Manufacture of computer, electronic and optical products460
- 27 Manufacture of electrical equipment489
- 28 Manufacture of machinery and equipment n.e.c.1,127
- 29 Manufacture of motor vehicles, trailers and semi-trailers307
- 30 Manufacture of other transport equipment132
- 31 Manufacture of furniture968
- 32 Other manufacturing960
- 33 Repair, maintenance and installation of machinery and equipment2,361
- 35 Electricity, gas, steam and air conditioning supply623
- 36 Water collection, treatment and supply41
- 37 Sewerage127
- 38 Waste collection, recovery and disposal activities664
- 39 Remediation activities and other waste management service activities112
- 41 Construction of residential and non-residential buildings12,390
- 42 Civil engineering2,400
- 43 Specialised construction activities35,294
- 46 Wholesale trade24,470
- 47 Retail trade26,224
- 49 Land transport and transport via pipelines7,319
- 50 Water transport339
- 51 Air transport173
- 52 Warehousing, storage and support activities for transportation2,364
- 53 Postal and courier activities573
- 55 Accommodation2,106
- 56 Food and beverage service activities16,014
- 58 Publishing activities768
- 59 Motion picture, video and television programme production, sound recording and music publishing activities1,456
- 60 Programming, broadcasting, news agency and other content distribution activities163
- 61 Telecommunication294
- 62 Computer programming, consultancy and related activities18,472
- 63 Computing infrastructure, data processing, hosting and other information service activities2,623
- 64 Financial service activities, except insurance and pension funding20,945
- 65 Insurance, reinsurance and pension funding, except compulsory social security152
- 66 Activities auxiliary to financial services and insurance activities5,256
- 68 Real estate activities32,646
- 69 Legal and accounting activities12,868
- 70 Activities of head offices and management consultancy35,926
- 71 Architectural and engineering activities; technical testing and analysis9,882
- 72 Scientific research and development599
- 73 Activities of advertising, market research and public relations6,897
- 74 Other professional, scientific and technical activities3,244
- 75 Veterinary activities1,234
- 77 Rental and leasing activities2,338
- 78 Employment activities1,219
- 79 Travel agency, tour operator and other reservation service and related activities644
- 80 Investigation and security activities301
- 81 Services to buildings and landscape activities5,098
- 82 Office administrative, office support and other business support activities9,438
- 84 Public administration and defence; compulsory social security98
- 85 Education2,506
- 86 Human health activities25,365
- 87 Residential care activities583
- 88 Social work activities without accommodation1,024
- 90 Arts creation and performing arts activities2,109
- 91 Libraries, archives, museums and other cultural activities129
- 92 Gambling and betting activities119
- 93 Sports activities and amusement and recreation activities2,717
- 94 Activities of membership organisations457
- 95 Repair and maintenance of computers, personal and household goods, and motor vehicles and motorcycles2,942
- 96 Personal service activities4,643
Municipalities with the most companies in the sector · Flanders
- 9052 Ghent (Zwijnaarde)11
- 9000 Ghent10
- 3500 Hasselt (Sint-Lambrechts-Herk)7
- 3001 Leuven (Heverlee)6
- 2300 Turnhout5
- 2870 Puurs-Sint-Amands (Breendonk, Liezele, Puurs, …)5
- 9031 Ghent (Drongen)5
- 9070 Destelbergen (Heusden)5
- 9800 Deinze (Astene, Bachte-Maria-Leerne, Gottem, …)5
- 2610 Antwerp (Wilrijk)4
- 3590 Diepenbeek4
- 8400 Ostend (Stene, Zandvoorde)4
Frequently asked questions
Which is the largest company in Manufacture of basic pharmaceutical products and pharmaceutical preparations in Flanders?
By total assets, it is Janssen Pharmaceutica (€21.6bn, financial year 2025).
How many companies in Manufacture of basic pharmaceutical products and pharmaceutical preparations in Flanders are ranked?
281 out of 300 active companies in the sector with their registered office in the area: those whose latest accounts are less than 3 years old.
Why does this ranking differ from other lists?
It uses each company's annual accounts as filed with the National Bank, not consolidated group accounts. A holding, a subsidiary or a purchasing entity can therefore appear separately. Only companies whose latest accounts are less than 3 years old are ranked.
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Active companies (legal entities) that have filed at least one set of annual accounts, based on the Crossroads Bank for Enterprises and the National Bank of Belgium. The sector is the main activity in the register; the municipality is that of the registered office. Data updated on 13 Nov 2026.