Ranking · East Flanders · NACE 72
Scientific research and development: the largest companies in East Flanders
As of 13 Nov 2026, 168 companies in Scientific research and development (NACE 72) in East Flanders publish total assets in recent accounts (financial years 2023 to 2026). The top 10 account for €8.46bn, out of €8.78bn for all of them; median total assets are 932,517 €. argenx leads with €7.01bn (financial year 2025).
Top 50 · Scientific research and development · East Flanders
Ranked by total assets in the latest filed accounts. This is a size criterion, not an assessment.
| # | Company | Total assets | Revenue | Equity | FTE | Year |
|---|---|---|---|---|---|---|
| 1 | argenx 9052 Ghent | €7.01bn | €3.80bn | €5.71bn | 510.9 | 2025 |
| 2 | Ablynx 9052 Ghent | €417.3m | €147.9m | €359.2m | 363.5 | 2025 |
| 3 | Vlaams Instituut voor Biotechnologie - Flanders Institute for Biotechnology 9052 Ghent | €323.7m | €52.6m | €172.4m | 928.4 | 2025 |
| 4 | Omega Pharma Innovation & Development 9050 Ghent | €246.6m | €16.3m | €240.2m | 38.2 | 2025 |
| 5 | Legend Biotech Belgium 9052 Ghent | €142.4m | €285.9m | €62.9m | 846.9 | 2025 |
| 6 | Devgen 9052 Ghent | €130.9m | €1.13m | €128.3m | 2.9 | 2025 |
| 7 | Ardena Holding 9030 Ghent | €87.1m | — | €84.2m | — | 2025 |
| 8 | Confo Therapeutics 9052 Ghent | €37.8m | 176,727 € | €33.3m | 59.0 | 2025 |
| 9 | Oystershell 9820 Merelbeke-Melle | €32.7m | €39.8m | €15.1m | 37.6 | 2025 |
| 10 | LO²CUS Gent 9052 Ghent | €29.4m | — | 532,347 € | 1.0 | 2024 |
| 11 | PharmaFluidics 9052 Ghent | €16.4m | €1.44m | €15.9m | 13.8 | 2025 |
| 12 | Biotalys 9051 Ghent | €16.3m | — | €9.87m | 58.2 | 2025 |
| 13 | Aphea.Bio 9052 Ghent | €16.2m | 14,118 € | €11.4m | 56.9 | 2025 |
| 14 | Viaverda 9070 Destelbergen | €14.2m | — | €9.68m | 93.3 | 2025 |
| 15 | Inari Agriculture, NV 9052 Ghent | €12.1m | €12.1m | €10.2m | 56.5 | 2025 |
| 16 | Microbial Resource Management Health 9052 Ghent | €11.7m | — | €6.93m | 22.8 | 2025 |
| 17 | Protealis 9052 Ghent | €11.1m | — | €9.06m | 17.2 | 2025 |
| 18 | AmphiStar 9052 Ghent | €10.1m | — | €6.40m | 13.5 | 2025 |
| 19 | Intrexon Actobiotics 9810 Nazareth-De Pinte | €8.76m | — | €8.59m | — | 2025 |
| 20 | Axithra 9052 Ghent | €8.60m | — | €8.01m | 4.2 | 2025 |
| 21 | ProDigest 9052 Ghent | €7.83m | — | €5.16m | 39.8 | 2025 |
| 22 | Orionis Biosciences 9052 Ghent | €6.88m | €11.6m | €4.92m | 36.3 | 2025 |
| 23 | Eurofins Amatsigroup 9052 Ghent | €6.78m | €17.5m | €3.65m | 76.4 | 2025 |
| 24 | Boehringer Ingelheim Veterinary Medicine Belgium NV 9940 Evergem | €6.51m | 0 € | €5.56m | 17.9 | 2025 |
| 25 | S-Biomedic 9052 Ghent | €5.94m | — | €1.85m | 12.2 | 2025 |
| 26 | Cryptobiotix 9052 Ghent | €5.70m | — | €3.70m | 15.8 | 2025 |
| 27 | Vervit 9080 Lochristi | €5.38m | — | 588,934 € | 16.0 | 2025 |
| 28 | BioLizard 9000 Ghent | €5.26m | — | €3.67m | 34.2 | 2025 |
| 29 | Belgisch Centrum voor Technologisch Onderzoek van Leidingen en Toebehoren 9090 Merelbeke-Melle | €5.05m | — | €4.22m | 12.6 | 2025 |
| 30 | Toku-E EU 9051 Ghent | €4.20m | — | 85,759 € | 11.8 | 2025 |
| 31 | CoreAalst 9300 Aalst | €4.16m | — | €1.96m | 1.8 | 2025 |
| 32 | Tanai Therapeutics 9051 Ghent | €3.87m | — | €3.56m | — | 2025 |
| 33 | ExeVir Bio 9052 Ghent | €3.76m | — | €3.67m | 1.8 | 2025 |
| 34 | Biomedical Application of Research in Infectious Diseases Control 9052 Ghent | €3.69m | — | €1.20m | 8.9 | 2025 |
| 35 | Dr.DHOORE 9520 Sint-Lievens-Houtem | €3.51m | — | €2.69m | — | 2025 |
| 36 | Dr. J. Bellon 9255 Buggenhout | €3.14m | — | €2.85m | — | 2025 |
| 37 | Elmace 9880 Aalter | €3.11m | — | €3.08m | — | 2025 |
| 38 | De Winter - Winne 9800 Deinze | €2.92m | — | €2.86m | — | 2025 |
| 39 | Dokter Geert De Bruecker - Neuropsychiatrie 9340 Lede | €2.74m | — | €2.26m | 0.2 | 2025 |
| 40 | Glibert Bart 9600 Ronse | €2.59m | — | €2.54m | — | 2025 |
| 41 | Dr. G. Degraeve, Psychiater 9990 Maldegem | €2.56m | — | €2.49m | — | 2025 |
| 42 | Apr. Biol. Inger Brandt 9280 Lebbeke | €2.44m | — | €2.40m | — | 2026 |
| 43 | Puxano 9000 Ghent | €2.43m | — | €2.10m | 5.5 | 2025 |
| 44 | Zymofix 9032 Ghent | €2.41m | — | €1.58m | 12.4 | 2025 |
| 45 | Dr. Coppens Greet, oogarts 9300 Aalst | €2.37m | — | €1.19m | — | 2025 |
| 46 | Ooginstituut 9300 Aalst | €2.35m | — | €1.68m | 11.8 | 2025 |
| 47 | Ziscoat 9160 Lokeren | €2.35m | — | €1.63m | 1.0 | 2025 |
| 48 | BAAC Vlaanderen 9968 Assenede | €2.34m | — | 905,507 € | 37.1 | 2025 |
| 49 | NewMilkLab 9052 Ghent | €2.32m | — | 497,664 € | 21.4 | 2025 |
| 50 | Asterion Research & Development 9000 Ghent | €2.31m | — | €1.64m | — | 2025 |
Ranking based on each company's own annual accounts (statutory, not consolidated): a subsidiary and its parent appear separately, and the ranking differs from lists based on consolidated group accounts.
“—”: not published. Small companies (micro and abridged accounts) do not have to publish their revenue.
Scientific research and development across Belgium → All sectors · East Flanders →
Other sectors · East Flanders
- 01 Crop and animal production, hunting and related service activities1,004
- 02 Forestry and logging43
- 08 Other mining and quarrying13
- 10 Manufacture of food products795
- 11 Manufacture of beverages98
- 13 Manufacture of textiles175
- 14 Manufacture of wearing apparel79
- 15 Manufacture of leather and related products of other materials16
- 16 Manufacture of wood and of products of wood and cork, except furniture; manufacture of articles of straw and plaiting materials238
- 17 Manufacture of paper and paper products52
- 18 Printing and reproduction of recorded media325
- 20 Manufacture of chemicals and chemical products147
- 21 Manufacture of basic pharmaceutical products and pharmaceutical preparations81
- 22 Manufacture of rubber and plastic products123
- 23 Manufacture of other non-metallic mineral products232
- 24 Manufacture of basic metals56
- 25 Manufacture of fabricated metal products, except machinery and equipment883
- 26 Manufacture of computer, electronic and optical products95
- 27 Manufacture of electrical equipment107
- 28 Manufacture of machinery and equipment n.e.c.255
- 29 Manufacture of motor vehicles, trailers and semi-trailers64
- 30 Manufacture of other transport equipment25
- 31 Manufacture of furniture228
- 32 Other manufacturing164
- 33 Repair, maintenance and installation of machinery and equipment519
- 35 Electricity, gas, steam and air conditioning supply131
- 36 Water collection, treatment and supply12
- 37 Sewerage32
- 38 Waste collection, recovery and disposal activities138
- 39 Remediation activities and other waste management service activities32
- 41 Construction of residential and non-residential buildings2,555
- 42 Civil engineering796
- 43 Specialised construction activities7,921
- 46 Wholesale trade4,896
- 47 Retail trade5,351
- 49 Land transport and transport via pipelines1,584
- 50 Water transport53
- 51 Air transport40
- 52 Warehousing, storage and support activities for transportation424
- 53 Postal and courier activities109
- 55 Accommodation383
- 56 Food and beverage service activities3,203
- 58 Publishing activities178
- 59 Motion picture, video and television programme production, sound recording and music publishing activities325
- 60 Programming, broadcasting, news agency and other content distribution activities35
- 61 Telecommunication49
- 62 Computer programming, consultancy and related activities4,087
- 63 Computing infrastructure, data processing, hosting and other information service activities515
- 64 Financial service activities, except insurance and pension funding4,362
- 65 Insurance, reinsurance and pension funding, except compulsory social security32
- 66 Activities auxiliary to financial services and insurance activities1,172
- 68 Real estate activities6,692
- 69 Legal and accounting activities2,828
- 70 Activities of head offices and management consultancy8,002
- 71 Architectural and engineering activities; technical testing and analysis2,350
- 73 Activities of advertising, market research and public relations1,387
- 74 Other professional, scientific and technical activities736
- 75 Veterinary activities251
- 77 Rental and leasing activities493
- 78 Employment activities226
- 79 Travel agency, tour operator and other reservation service and related activities140
- 80 Investigation and security activities61
- 81 Services to buildings and landscape activities1,083
- 82 Office administrative, office support and other business support activities2,177
- 84 Public administration and defence; compulsory social security32
- 85 Education534
- 86 Human health activities5,696
- 87 Residential care activities132
- 88 Social work activities without accommodation183
- 90 Arts creation and performing arts activities461
- 91 Libraries, archives, museums and other cultural activities18
- 92 Gambling and betting activities33
- 93 Sports activities and amusement and recreation activities551
- 94 Activities of membership organisations107
- 95 Repair and maintenance of computers, personal and household goods, and motor vehicles and motorcycles635
- 96 Personal service activities847
Municipalities with the most companies in the sector · East Flanders
- 9052 Ghent (Zwijnaarde)29
- 9000 Ghent22
- 9300 Aalst11
- 9051 Ghent (Afsnee, Sint-Denijs-Westrem)6
- 9940 Evergem (Ertvelde, Kluizen, Sleidinge)6
- 9050 Ghent (Gentbrugge, Ledeberg)5
- 9080 Lochristi (Beervelde, Zaffelare, Zeveneken)5
- 9200 Dendermonde (Appels, Baasrode, Grembergen, …)5
- 9700 Oudenaarde (Bevere, Edelare, Eine, …)5
- 9070 Destelbergen (Heusden)4
- 9800 Deinze (Astene, Bachte-Maria-Leerne, Gottem, …)4
- 9820 Merelbeke-Melle (Bottelare, Lemberge, Melsen, …)4
Frequently asked questions
Which is the largest company in Scientific research and development in East Flanders?
By total assets, it is argenx (€7.01bn, financial year 2025).
How many companies in Scientific research and development in East Flanders are ranked?
168 out of 170 active companies in the sector with their registered office in the area: those whose latest accounts are less than 3 years old.
Why does this ranking differ from other lists?
It uses each company's annual accounts as filed with the National Bank, not consolidated group accounts. A holding, a subsidiary or a purchasing entity can therefore appear separately. Only companies whose latest accounts are less than 3 years old are ranked.
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Active companies (legal entities) that have filed at least one set of annual accounts, based on the Crossroads Bank for Enterprises and the National Bank of Belgium. The sector is the main activity in the register; the municipality is that of the registered office. Data updated on 13 Nov 2026.